| 1 | October 02, 2020 CET: 19:45 | Fenerbahce Beko Istanbul FBI | 77-63 | Crvena Zvezda mts Belgrade CZV |
| 2 | October 08, 2020 CET: 19:30 | Anadolu Efes Istanbul EFE | 71-80 | Fenerbahce Beko Istanbul FBI |
| 3 | October 14, 2020 CET: 19:45 | Fenerbahce Beko Istanbul FBI | 77-78 | CSKA Moscow CSK |
| 4 | October 16, 2020 CET: 19:45 | Fenerbahce Beko Istanbul FBI | 71-75 | FC Bayern Munich BAY |
| 5 | October 22, 2020 CET: 20:00 | Panathinaikos OPAP Athens PAO | 82-68 | Fenerbahce Beko Istanbul FBI |
| 6 | October 29, 2020 CET: 20:05 | Maccabi Playtika Tel Aviv MTA | 65-75 | Fenerbahce Beko Istanbul FBI |
| 7 | November 06, 2020 CET: 18:45 | Fenerbahce Beko Istanbul FBI | 83-71 | Khimki Moscow Region KHI |
| 8 | November 12, 2020 CET: 21:00 | FC Barcelona BAR | 97-55 | Fenerbahce Beko Istanbul FBI |
| 9 | November 17, 2020 CET: 20:30 | TD Systems Baskonia Vitoria-Gasteiz TDB | 86-68 | Fenerbahce Beko Istanbul FBI |
| 10 | November 20, 2020 CET: 21:00 | Real Madrid RMB | 94-74 | Fenerbahce Beko Istanbul FBI |
| 11 | November 27, 2020 CET: 18:45 | Fenerbahce Beko Istanbul FBI | 86-90 | Valencia Basket VAL |
| 12 | December 03, 2020 CET: 18:00 | Zenit St Petersburg ZEN | 65-73 | Fenerbahce Beko Istanbul FBI |
| 13 | December 10, 2020 CET: 20:00 | ALBA Berlin ALB | 89-63 | Fenerbahce Beko Istanbul FBI |
| 14 | December 15, 2020 CET: 18:45 | Fenerbahce Beko Istanbul FBI | 71-79 | AX Armani Exchange Milan AXM |
| 15 | December 17, 2020 CET: 19:00 | Zalgiris Kaunas ZAL | 99-62 | Fenerbahce Beko Istanbul FBI |
| 16 | December 23, 2020 CET: 18:45 | Fenerbahce Beko Istanbul FBI | 84-77 | Olympiacos Piraeus OLY |
| 17 | December 30, 2020 CET: 18:45 | Fenerbahce Beko Istanbul FBI | 81-59 | LDLC ASVEL Villeurbanne ASV |
| 18 | January 07, 2021 CET: 19:00 | Crvena Zvezda mts Belgrade CZV | 71-73 | Fenerbahce Beko Istanbul FBI |
| 19 | January 12, 2021 CET: 18:45 | Fenerbahce Beko Istanbul FBI | 96-76 | TD Systems Baskonia Vitoria-Gasteiz TDB |
| 20 | January 15, 2021 CET: 18:45 | Fenerbahce Beko Istanbul FBI | 100-74 | Panathinaikos OPAP Athens PAO |
| 21 | January 22, 2021 CET: 18:00 | CSKA Moscow CSK | 83-89 | Fenerbahce Beko Istanbul FBI |
| 22 | January 26, 2021 CET: 18:45 | Fenerbahce Beko Istanbul FBI | 82-75 | Maccabi Playtika Tel Aviv MTA |
| 23 | January 28, 2021 CET: 18:00 | Khimki Moscow Region KHI | 76-107 | Fenerbahce Beko Istanbul FBI |
| 24 | February 05, 2021 CET: 18:45 | Fenerbahce Beko Istanbul FBI | 92-84 | Zenit St Petersburg ZEN |
| 25 | February 19, 2021 CET: 18:45 | Fenerbahce Beko Istanbul FBI | 89-84 | ALBA Berlin ALB |
| 26 | February 26, 2021 CET: 18:45 | Fenerbahce Beko Istanbul FBI | 74-106 | Anadolu Efes Istanbul EFE |
| 27 | March 03, 2021 CET: 20:45 | AX Armani Exchange Milan AXM | 92-100 | Fenerbahce Beko Istanbul FBI |
| 28 | March 05, 2021 CET: 20:45 | LDLC ASVEL Villeurbanne ASV | 86-90 | Fenerbahce Beko Istanbul FBI |
| 29 | March 12, 2021 CET: 21:00 | Valencia Basket VAL | 0-0 | Fenerbahce Beko Istanbul FBI |
| 30 | March 18, 2021 CET: 18:45 | Fenerbahce Beko Istanbul FBI | 0-0 | Zalgiris Kaunas ZAL |
| 31 | March 26, 2021 CET: 20:00 | Olympiacos Piraeus OLY | 0-0 | Fenerbahce Beko Istanbul FBI |
| 32 | March 31, 2021 CET: 20:30 | FC Bayern Munich BAY | 0-0 | Fenerbahce Beko Istanbul FBI |
| 33 | April 02, 2021 CET: 19:45 | Fenerbahce Beko Istanbul FBI | 0-0 | FC Barcelona BAR |
| 34 | April 08, 2021 CET: 19:45 | Fenerbahce Beko Istanbul FBI | 0-0 | Real Madrid RMB |
