| 1 | October 01, 2020 CET: 20:00 | Olympiacos Piraeus OLY | 67-68 | Zalgiris Kaunas ZAL |
| 2 | October 09, 2020 CET: 20:00 | Panathinaikos OPAP Athens PAO | 71-78 | Olympiacos Piraeus OLY |
| 3 | October 14, 2020 CET: 18:30 | Olympiacos Piraeus OLY | 86-75 | AX Armani Exchange Milan AXM |
| 4 | October 16, 2020 CET: 20:00 | Olympiacos Piraeus OLY | 85-82 | Maccabi Playtika Tel Aviv MTA |
| 5 | October 23, 2020 CET: 20:30 | FC Bayern Munich BAY | 74-68 | Olympiacos Piraeus OLY |
| 6 | October 30, 2020 CET: 20:00 | Olympiacos Piraeus OLY | 79-84 | Anadolu Efes Istanbul EFE |
| 7 | November 05, 2020 CET: 18:00 | Zenit St Petersburg ZEN | 66-75 | Olympiacos Piraeus OLY |
| 8 | November 12, 2020 CET: 20:00 | Olympiacos Piraeus OLY | 75-71 | ALBA Berlin ALB |
| 10 | January 19, 2021 CET: 20:45 | LDLC ASVEL Villeurbanne ASV | 0-0 | Olympiacos Piraeus OLY |
| 11 | November 26, 2020 CET: 20:00 | Olympiacos Piraeus OLY | 76-90 | TD Systems Baskonia Vitoria-Gasteiz TDB |
| 12 | December 03, 2020 CET: 18:00 | CSKA Moscow CSK | 80-61 | Olympiacos Piraeus OLY |
| 13 | December 10, 2020 CET: 19:00 | Crvena Zvezda mts Belgrade CZV | 79-81 | Olympiacos Piraeus OLY |
| 14 | December 16, 2020 CET: 20:30 | Olympiacos Piraeus OLY | 85-96 | Valencia Basket VAL |
| 15 | December 18, 2020 CET: 20:00 | Olympiacos Piraeus OLY | 82-86 | Real Madrid RMB |
| 16 | December 23, 2020 CET: 18:45 | Fenerbahce Beko Istanbul FBI | 84-77 | Olympiacos Piraeus OLY |
| 17 | December 29, 2020 CET: 18:00 | Khimki Moscow Region KHI | 88-105 | Olympiacos Piraeus OLY |
| 18 | January 08, 2021 CET: 20:00 | Olympiacos Piraeus OLY | 84-82 | FC Bayern Munich BAY |
| 19 | January 12, 2021 CET: 20:05 | Maccabi Playtika Tel Aviv MTA | 87-89 | Olympiacos Piraeus OLY |
| 20 | January 15, 2021 CET: 20:30 | Olympiacos Piraeus OLY | 63-69 | LDLC ASVEL Villeurbanne ASV |
| 21 | January 22, 2021 CET: 19:00 | Zalgiris Kaunas ZAL | 81-79 | Olympiacos Piraeus OLY |
| 22 | January 26, 2021 CET: 20:45 | AX Armani Exchange Milan AXM | 90-79 | Olympiacos Piraeus OLY |
| 23 | January 28, 2021 CET: 20:00 | Olympiacos Piraeus OLY | 74-76 | FC Barcelona BAR |
| 24 | February 05, 2021 CET: 20:00 | Olympiacos Piraeus OLY | 77-88 | Panathinaikos OPAP Athens PAO |
| 25 | February 18, 2021 CET: 18:30 | Anadolu Efes Istanbul EFE | 76-53 | Olympiacos Piraeus OLY |
| 26 | February 25, 2021 CET: 20:00 | Olympiacos Piraeus OLY | 74-75 | CSKA Moscow CSK |
| 27 | March 03, 2021 CET: 21:00 | TD Systems Baskonia Vitoria-Gasteiz TDB | 91-66 | Olympiacos Piraeus OLY |
| 28 | March 05, 2021 CET: 20:00 | Olympiacos Piraeus OLY | 94-79 | Crvena Zvezda mts Belgrade CZV |
| 29 | March 12, 2021 CET: 20:00 | Olympiacos Piraeus OLY | 0-0 | Zenit St Petersburg ZEN |
| 30 | March 18, 2021 CET: 20:00 | ALBA Berlin ALB | 0-0 | Olympiacos Piraeus OLY |
| 31 | March 26, 2021 CET: 20:00 | Olympiacos Piraeus OLY | 0-0 | Fenerbahce Beko Istanbul FBI |
| 32 | March 31, 2021 CET: 21:00 | Valencia Basket VAL | 0-0 | Olympiacos Piraeus OLY |
| 33 | April 02, 2021 CET: 21:00 | Real Madrid RMB | 0-0 | Olympiacos Piraeus OLY |
| 34 | April 09, 2021 CET: 20:00 | Olympiacos Piraeus OLY | 0-0 | Khimki Moscow Region KHI |
