| 1 | October 01, 2020 CET: 19:30 | Anadolu Efes Istanbul EFE | 69-73 | Zenit St Petersburg ZEN |
| 2 | October 08, 2020 CET: 19:30 | Anadolu Efes Istanbul EFE | 71-80 | Fenerbahce Beko Istanbul FBI |
| 3 | October 13, 2020 CET: 20:00 | ALBA Berlin ALB | 72-93 | Anadolu Efes Istanbul EFE |
| 4 | October 15, 2020 CET: 19:00 | Zalgiris Kaunas ZAL | 89-73 | Anadolu Efes Istanbul EFE |
| 6 | October 30, 2020 CET: 20:00 | Olympiacos Piraeus OLY | 79-84 | Anadolu Efes Istanbul EFE |
| 7 | November 05, 2020 CET: 18:30 | Anadolu Efes Istanbul EFE | 91-89 | Maccabi Playtika Tel Aviv MTA |
| 8 | November 13, 2020 CET: 20:00 | Panathinaikos OPAP Athens PAO | 77-80 | Anadolu Efes Istanbul EFE |
| 9 | November 17, 2020 CET: 18:30 | Anadolu Efes Istanbul EFE | 71-74 | FC Bayern Munich BAY |
| 10 | November 19, 2020 CET: 18:00 | Khimki Moscow Region KHI | 77-105 | Anadolu Efes Istanbul EFE |
| 11 | November 26, 2020 CET: 19:00 | Crvena Zvezda mts Belgrade CZV | 64-75 | Anadolu Efes Istanbul EFE |
| 12 | December 04, 2020 CET: 17:30 | Anadolu Efes Istanbul EFE | 59-77 | TD Systems Baskonia Vitoria-Gasteiz TDB |
| 13 | December 10, 2020 CET: 21:00 | Valencia Basket VAL | 76-74 | Anadolu Efes Istanbul EFE |
| 14 | December 15, 2020 CET: 18:00 | CSKA Moscow CSK | 100-65 | Anadolu Efes Istanbul EFE |
| 15 | December 17, 2020 CET: 18:30 | Anadolu Efes Istanbul EFE | 69-72 | AX Armani Exchange Milan AXM |
| 16 | December 22, 2020 CET: 18:30 | Anadolu Efes Istanbul EFE | 86-79 | FC Barcelona BAR |
| 17 | December 29, 2020 CET: 18:30 | Anadolu Efes Istanbul EFE | 65-73 | Real Madrid RMB |
| 18 | January 08, 2021 CET: 20:45 | LDLC ASVEL Villeurbanne ASV | 80-102 | Anadolu Efes Istanbul EFE |
| 19 | January 12, 2021 CET: 18:30 | Anadolu Efes Istanbul EFE | 84-76 | ALBA Berlin ALB |
| 20 | January 14, 2021 CET: 18:30 | Anadolu Efes Istanbul EFE | 99-60 | Khimki Moscow Region KHI |
| 21 | January 21, 2021 CET: 18:00 | Zenit St Petersburg ZEN | 85-78 | Anadolu Efes Istanbul EFE |
| 22 | January 26, 2021 CET: 18:30 | Anadolu Efes Istanbul EFE | 86-72 | Crvena Zvezda mts Belgrade CZV |
| 23 | January 28, 2021 CET: 20:05 | Maccabi Playtika Tel Aviv MTA | 0-0 | Anadolu Efes Istanbul EFE |
| 24 | February 04, 2021 CET: 21:00 | FC Barcelona BAR | 86-88 | Anadolu Efes Istanbul EFE |
| 25 | February 18, 2021 CET: 18:30 | Anadolu Efes Istanbul EFE | 76-53 | Olympiacos Piraeus OLY |
| 26 | February 26, 2021 CET: 18:45 | Fenerbahce Beko Istanbul FBI | 74-106 | Anadolu Efes Istanbul EFE |
| 27 | March 02, 2021 CET: 18:30 | Anadolu Efes Istanbul EFE | 99-83 | Valencia Basket VAL |
| 28 | March 04, 2021 CET: 18:30 | Anadolu Efes Istanbul EFE | 100-70 | CSKA Moscow CSK |
| 29 | March 12, 2021 CET: 18:30 | Anadolu Efes Istanbul EFE | 0-0 | Zalgiris Kaunas ZAL |
| 30 | March 19, 2021 CET: 20:30 | FC Bayern Munich BAY | 0-0 | Anadolu Efes Istanbul EFE |
| 31 | March 25, 2021 CET: 18:30 | Anadolu Efes Istanbul EFE | 0-0 | Panathinaikos OPAP Athens PAO |
| 32 | March 30, 2021 CET: 21:00 | Real Madrid RMB | 0-0 | Anadolu Efes Istanbul EFE |
| 33 | April 01, 2021 CET: 21:00 | TD Systems Baskonia Vitoria-Gasteiz TDB | 0-0 | Anadolu Efes Istanbul EFE |
| 34 | April 09, 2021 CET: 20:45 | AX Armani Exchange Milan AXM | 0-0 | Anadolu Efes Istanbul EFE |
