| 1 | October 02, 2020 CET: 21:00 | TD Systems Baskonia Vitoria-Gasteiz TDB | 76-63 | Real Madrid RMB |
| 2 | October 09, 2020 CET: 19:00 | Crvena Zvezda mts Belgrade CZV | 90-73 | TD Systems Baskonia Vitoria-Gasteiz TDB |
| 3 | November 23, 2020 CET: 19:30 | TD Systems Baskonia Vitoria-Gasteiz TDB | 70-77 | Zenit St Petersburg ZEN |
| 4 | October 16, 2020 CET: 21:00 | TD Systems Baskonia Vitoria-Gasteiz TDB | 77-60 | Khimki Moscow Region KHI |
| 5 | January 05, 2021 CET: 19:00 | ALBA Berlin ALB | 0-0 | TD Systems Baskonia Vitoria-Gasteiz TDB |
| 6 | October 30, 2020 CET: 20:30 | TD Systems Baskonia Vitoria-Gasteiz TDB | 71-72 | FC Barcelona BAR |
| 7 | November 05, 2020 CET: 20:30 | TD Systems Baskonia Vitoria-Gasteiz TDB | 86-88 | LDLC ASVEL Villeurbanne ASV |
| 8 | November 12, 2020 CET: 18:00 | CSKA Moscow CSK | 89-86 | TD Systems Baskonia Vitoria-Gasteiz TDB |
| 9 | November 17, 2020 CET: 20:30 | TD Systems Baskonia Vitoria-Gasteiz TDB | 86-68 | Fenerbahce Beko Istanbul FBI |
| 10 | November 19, 2020 CET: 20:30 | TD Systems Baskonia Vitoria-Gasteiz TDB | 93-72 | Panathinaikos OPAP Athens PAO |
| 11 | November 26, 2020 CET: 20:00 | Olympiacos Piraeus OLY | 76-90 | TD Systems Baskonia Vitoria-Gasteiz TDB |
| 12 | December 04, 2020 CET: 17:30 | Anadolu Efes Istanbul EFE | 59-77 | TD Systems Baskonia Vitoria-Gasteiz TDB |
| 13 | December 10, 2020 CET: 21:00 | TD Systems Baskonia Vitoria-Gasteiz TDB | 63-67 | Maccabi Playtika Tel Aviv MTA |
| 14 | December 15, 2020 CET: 19:00 | Zalgiris Kaunas ZAL | 92-73 | TD Systems Baskonia Vitoria-Gasteiz TDB |
| 15 | December 18, 2020 CET: 19:30 | FC Bayern Munich BAY | 77-66 | TD Systems Baskonia Vitoria-Gasteiz TDB |
| 16 | December 23, 2020 CET: 20:45 | AX Armani Exchange Milan AXM | 79-84 | TD Systems Baskonia Vitoria-Gasteiz TDB |
| 17 | December 29, 2020 CET: 21:00 | TD Systems Baskonia Vitoria-Gasteiz TDB | 71-70 | Valencia Basket VAL |
| 18 | January 07, 2021 CET: 21:00 | TD Systems Baskonia Vitoria-Gasteiz TDB | 95-93 | CSKA Moscow CSK |
| 19 | January 12, 2021 CET: 18:45 | Fenerbahce Beko Istanbul FBI | 96-76 | TD Systems Baskonia Vitoria-Gasteiz TDB |
| 20 | January 14, 2021 CET: 20:05 | Maccabi Playtika Tel Aviv MTA | 91-82 | TD Systems Baskonia Vitoria-Gasteiz TDB |
| 21 | January 22, 2021 CET: 21:00 | TD Systems Baskonia Vitoria-Gasteiz TDB | 77-84 | ALBA Berlin ALB |
| 22 | January 27, 2021 CET: 20:45 | LDLC ASVEL Villeurbanne ASV | 83-77 | TD Systems Baskonia Vitoria-Gasteiz TDB |
| 23 | January 29, 2021 CET: 21:00 | TD Systems Baskonia Vitoria-Gasteiz TDB | 81-68 | Zalgiris Kaunas ZAL |
| 24 | February 05, 2021 CET: 21:00 | Real Madrid RMB | 64-84 | TD Systems Baskonia Vitoria-Gasteiz TDB |
| 25 | February 18, 2021 CET: 18:00 | Khimki Moscow Region KHI | 67-89 | TD Systems Baskonia Vitoria-Gasteiz TDB |
| 26 | February 26, 2021 CET: 21:00 | TD Systems Baskonia Vitoria-Gasteiz TDB | 87-67 | Crvena Zvezda mts Belgrade CZV |
| 27 | March 03, 2021 CET: 21:00 | TD Systems Baskonia Vitoria-Gasteiz TDB | 91-66 | Olympiacos Piraeus OLY |
| 28 | March 05, 2021 CET: 21:00 | FC Barcelona BAR | 71-57 | TD Systems Baskonia Vitoria-Gasteiz TDB |
| 29 | March 12, 2021 CET: 21:00 | TD Systems Baskonia Vitoria-Gasteiz TDB | 0-0 | FC Bayern Munich BAY |
| 30 | March 18, 2021 CET: 18:00 | Zenit St Petersburg ZEN | 0-0 | TD Systems Baskonia Vitoria-Gasteiz TDB |
| 31 | March 26, 2021 CET: 21:00 | TD Systems Baskonia Vitoria-Gasteiz TDB | 0-0 | AX Armani Exchange Milan AXM |
| 32 | March 30, 2021 CET: 20:00 | Panathinaikos OPAP Athens PAO | 0-0 | TD Systems Baskonia Vitoria-Gasteiz TDB |
| 33 | April 01, 2021 CET: 21:00 | TD Systems Baskonia Vitoria-Gasteiz TDB | 0-0 | Anadolu Efes Istanbul EFE |
| 34 | April 08, 2021 CET: 21:00 | Valencia Basket VAL | 0-0 | TD Systems Baskonia Vitoria-Gasteiz TDB |
